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Intravitreal anti-VEGF agents such as avastin, lucentis and macugen with wet macular degeneration.  (Christoforidis) The project of radiolabeling of anti-VEGF agents was actively continued these past 12 months. The results of the work have received national and international

By L. E. Leguire Ph.D., MBA “What do you mean she has lazy eye in both eyes!” exclaimed Judy’s mother. Shocked, she sat in disbelief as the eye doctor explained the results of Judy’s comprehensive eye exam. “Isn’t lazy eye a problem with one eye and

The Influence of Biomechanical Ocular Properties and Ocular Pulse Amplitude in Glaucoma.  (Roberts, Weber, Fleming, and Sawchyn) Work will continue on the hypothesis proposed previously, describing the influence of the variation in intraocular pressure caused by the heart beat

The Investigation of Multifunctional Microbubbles for Sustained Release in Intravitreal Injection of anti-VEGF agents.  (Xu, Letson, Roberts) The goal of this ongoing project is to investigate novel methods of encapsulation of anti-VEGF agents in the fabrication of microbubbles

Corneal Biomechanical and Hydration Model before and after Refractive Surgery.  (Grzybowski and Roberts) A combination of topography, wavefront, reflectivity, and autorefraction data will be used to create a model of corneal biomechanical response to refractive surgery that

By L. E. Leguire Ph.D., MBA Vision Recovery in the Amblyopic Eye Following Loss of Vision in the Good Eye In older children as well an in adults with permanent amblyopia, it is strongly recommended that the amblyopic patient wear glasses to protect the remaining good eye because

Cellular Response of Trabecular Meshwork Cells on Micro/Nano Scale Substrates.  (Zhao, Weber, Roberts) The hydraulic conductivity response of primary cultures of trabecular meshwork (TM) endothelial cells to laser irradiation has been studied for many years. In the past year,

Corneal Biomechanical Properties in Keratoconus.  (Roberts) Work will continue on the new hypothesis proposed for biomechanical progression in Keratoconus, in which a confined corneal region has a reduction in elastic modulus. This confined region bulges due to a specific

By L. E. Leguire Ph.D., MBA Amblyopia, commonly known as lazy eye, is the leading cause of vision loss in children and affects about 2 – 4% of the population.  Every year, about 120,000 children in the United States develop amblyopia.  Amblyopia is defined as a loss of

By L. E. Leguire Ph.D., MBA A recent article entitled “Why is Compliance with Patching Therapy for Amblyopia so Hard? by Dixon-Woods and Gottlob (Arch Dis Child 2006, p491-494) may be of interest to parents of amblyopic children undergoing patching therapy. The authors